The St. Regis Hotel, situated within blocks of the White House, is an American version of an Italian Renaissance palazzo. True to form, the St. Regis Restaurant creates a grand setting worthy of the Medici; picture glistening crystal and gold chandeliers, ceiling-high windows draped with butternut-colored silk, and paneled walls with intricately carved detail. The hotel has plenty of ways to relax, too – try the Library Lounge, lined with old books and plasma screen TVs in an interesting blend of classic and modern. For a noteworthy splurge, reserve a place on the Astor Floor, which provides doting butler service. This includes complimentary clothes pressings, help with unpacking and other flagrantly indulgent assistance. Guest rooms at the St. Regis are bathed in opulence, from the honey-colored furnishings to the soft, Regency-style furnishings. From your jumping off point at 16th Street and West, traverse storied Lafayette Square and Capitol Hill. You’ll also be near the White House, the Renwick Gallery and the Corcoran Gallery of Art.